The city of Ann Arbor, Michigan, currently has 3 active clinical trials seeking participants for Osteoarthritis research studies.
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee
Recruiting
This clinical trial is being done to better understand how daily treatment with Tetrahydrocannabinol (THC), Cannabidiol (CBD), or the combination of CBD plus THC affects knee osteoarthritis pain and other related symptoms. Consented participants will have a screening period and visit (up to 30 days to treatment start). If participants pass the screening phase, they will be randomly assigned to take one of the investigational study drugs. For this study, participants will not know when or if the... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
03/21/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Osteoarthritis, Knee, Osteoarthritis of the Knee
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
Recruiting
The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflammation and other related symptoms, after knee replacement surgery. The information collected in this study is necessary to help understand whether CBD may be a useful medication before and/or after surgery. The study hypothesis is that CBD exerts opioid-sparing effects through anti-inflammatory, analgesic, and anxiolytic mechanisms.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/19/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Knee Replacement Surgery, Osteoarthritis, Knee